Il15ra Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comIl15ra Polyclonal Antibody for Mouse(Mus musculus)

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Il15ra (Gene name),

Interleukin-15 receptor subunit alpha (Protein name ), I15RA_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Il15ra;

Protein name:

Interleukin-15 receptor subunit alpha(IL-15 receptor subunit alpha;IL-15R-alpha;IL-15RA);

Alternative:

CD:

CD215;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

The interleukin-15 receptor IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL15RA also self-associates. Interacts with SYK.

Function:

High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Signal transduction seems to involve STAT3, STAT5, STAT6, JAK2 and SYK. Expression of different isoforms may alter or interfere with signal transduction.

Subcellular Location:

Soluble interleukin-15 receptor subunit alpha Secreted extracellular space

Protein Attributes:

Sequence length:

263

Sequence:

50:

100:

150:

200:

250:

263:

VRASSKEDED | TGA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q60819

UniGene:

Mm.200196

String:

Q60819

Pfam:

PF00084

KEGG:

mmu:16169

Uniprot:

Q60819

FOR

ELISA Kit for Mouse IL-15 receptor subunit alpha

Cat.:

E1035m

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Packing:

96T

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ELISA Kit for Mouse IL-15 receptor subunit alpha

Cat.:

E1035h

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96T

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CLIA Kit for Mouse IL-15 receptor subunit alpha

Cat.:

U1035h

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Looking for manual.

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Packing:

96T

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CLIA Kit for Mouse IL-15 receptor subunit alpha

Cat.:

U1035m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Mouse IL-15 receptor subunit alpha

Cat.:

P1035Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse IL-15 receptor subunit alpha

Cat.:

P1035Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse IL-15 receptor subunit alpha

Protein for Mouse IL-15 receptor subunit alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor."
Giri J.G. , Kumaki S. , Ahdieh M. , Friend D.J. , Loomis A. , Shanebeck K. , DuBose R. , Cosman D. , Park L.S. , Anderson D.M.
EMBO J.14:3654-3663(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);LIGAND-BINDING;SUBUNIT;TISSUE SPECIFICITY
2.

"Cytokine requirements for the growth and development of mouse NK cells in vitro."
Toomey J.A. , Gays F. , Foster D. , Brooks C.G.
J. Leukoc. Biol.74:233-242(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3; 4 AND 5);TISSUE SPECIFICITY
strain: C57BL/6.
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5)
strain: FVB/N.
tissue: Mammary tumor.
5.

"Mast cells express novel functional IL-15 receptor alpha isoforms."
Bulanova E. , Budagian V. , Orinska Z. , Krause H. , Paus R. , Bulfone-Paus S.
J. Immunol.170:5045-5055(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS 3; 4 AND 6);FUNCTION;SUBCELLULAR LOCATION;GLYCOSYLATION;INTERACTION WITH SYK
6.

Krause H. , Paus R. , Orinska Z. , Bulfone-Paus S.
J. Immunol.186:2682-2682(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM;RETRACTION
7.

"Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17)."
Budagian V. , Bulanova E. , Orinska Z. , Ludwig A. , Rose-John S. , Saftig P. , Borden E.C. , Bulfone-Paus S.
J. Biol. Chem.279:40368-40375(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING BY ADAM17
8.

"Crystal Structure of the interleukin-15.interleukin-15 receptor alpha complex: insights into trans and cis presentation."
Olsen S.K. , Ota N. , Kishishita S. , Kukimoto-Niino M. , Murayama K. , Uchiyama H. , Toyama M. , Terada T. , Shirouzu M. , Kanagawa O. , Yokoyama S.
J. Biol. Chem.282:37191-37204(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.19 ANGSTROMS) OF 33-103 IN COMPLEX WITH IL15;FUNCTION;DISULFIDE BONDS

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